About GRIN Therapeutics

Our mission

“GRIN therapeutics is dedicated to the research and development of precision therapeutics for pediatric neurodevelopmental disorders caused by NMDA receptor dysfunction.”

The history of GRIN Therapeutics

GRIN Therapeutics was founded when Dr. Pierandrea Muglia met the GRIN community at the 2019 CFERV Conference on GRIN Variants at Emory University, in Atlanta. Dr. Muglia came arrived knowing that radiprodil had a mechanism suggesting it might help patients with gain of function genetic variants in GRIN2B. What he didn’t expect was the maturity of the work produced by the GRIN community—from clinicians, researchers, advocates, and families working together. This inspired him to form GRIN Therapeutics to develop potential a treatment for the GRIN community. This passion has fed and inspired our small, patient-focused team. Early success in GRIN-NDD has spurred exploration into other neurodevelopmental disorders involving NMDA receptor dysregulation.

Leadership team

The GRIN Therapeutics leadership team was chosen for its deep domain expertise in advancing treatments for neurological disorders, particularly for those involving seizures, from early clinical development through regulatory approval and beyond.

Bruce Leuchter, MD
Bruce Leuchter, MD
President, CEO, Board Member

Michael A. Panzara, MD, MPH
Michael A. Panzara, MD, MPH
Chief Medical Officer

Elliott Ruiz, MBA
Elliott Ruiz, MBA
Senior Vice President, Finance & Operations

Jason Lettiere
Jason Lettiere
Senior Vice President, Corporate & Business Development

Anne-Marie Li-Kwai-Cheung
Anne-Marie Li-Kwai-Cheung
Senior Vice President, Development, Regulatory, and Quality

Carlos Martin
Carlos Martin
Chief Commercial Officer

Board of Directors

GRIN therapeutics, Inc is an affiliate of Neurvati Neurosciences, a Blackstone Life Sciences portfolio company.

Deborah Dunsire, MD
Deborah Dunsire, MD
Chairwoman, Board Member

Jacopo Andreose, PhD
Jacopo Andreose, PhD
Board Member

Gail Farfel, PhD
Gail Farfel, PhD
Board Member

Jonathan Freeman, PhD
Jonathan Freeman, PhD
Board Member

Nicholas Galakatos, PhD
Nicholas Galakatos, PhD
Board Member

Pierre Jacquet, MD, PhD
Pierre Jacquet, MD, PhD
Board Member

Kiran Reddy, MD
Kiran Reddy, MD
Board Member