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Advancing a targeted approach to the treatment of GRIN-related disorders and other types of pediatric epilepsy

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About GRIN Therapeutics

Neurodevelopmental disorders represent significant areas of unmet need in healthcare. People affected by these disorders, predominantly children and young adults, can face a range of severe and devastating symptoms. In many cases, there are only limited or no treatments available. GRIN Therapeutics is dedicated to the research and development of precision therapeutics for pediatric neurodevelopmental disorders with the goal of bringing hope to patients and caregivers.

GRIN Therapeutics is advancing promising research and development to assess the safety and efficacy of the investigational therapy radiprodil for the treatment of serious neurodevelopmental disorders including GRIN-related neurodevelopmental disorder (GRIN-NDD), tuberous sclerosis complex (TSC), and focal cortical dysplasia (FCD).

In many cases, pediatric neurodevelopmental disorders are rare diseases that are not widely known or understood. In our effort to potentially bring new options to people living with pediatric neurodevelopmental disorders, GRIN Therapeutics is privileged to work with many of the global leaders in research, patient care, and advocacy to help build broader awareness of the impact of these disorders among patients, caregivers and communities.

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Our Science

Discover our clinical development program centered on our lead asset, radiprodil, and how it has the potential to make a difference in people living with rare, neurodevelopmental disorders with an underlying disease pathology involving dysregulated NMDA receptor activity.

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Disease State

NMDA receptor signaling is an essential component of establishing and maintaining excitatory/inhibitory balance in the brain and dysregulation of NMDA receptor activity may contribute to the underlying mechanisms of neurodevelopmental disorders.

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Featured News & Events

Neurvati Neurosciences Appoints Carlos Martin as Chief Commercial Officer

November 13, 2025 – Neurvati Neurosciences, the neuroscience development platform of Blackstone Life Sciences, today announced the appointment of Carlos Martin as Chief Commercial Officer (CCO).

GRIN Therapeutics Presents Multiple Clinical Development Updates for Radiprodil at 2025
ILAE International Epilepsy Congress

September 2, 2025 – GRIN Therapeutics, Inc., a leader in the development of targeted disease-specific therapies to treat serious neurodevelopmental disorders, today announced presentations of three abstracts during the International League Against Epilepsy’s (ILAE) 36th International Epilepsy Congress in Lisbon, Portugal.

Neurvati Neurosciences and GRIN Therapeutics Announce Appointment of Gail Farfel, PhD to Their Boards of Directors

June 18, 2025 – Neurvati Neurosciences, a clinical-stage biotechnology company dedicated to bringing a new generation of therapies to people affected by neurological and psychiatric disorders, and GRIN Therapeutics, Inc., a leader in the development of therapies to treat serious neurodevelopmental disorders, today announced the appointment of Gail M. Farfel, PhD to the board of directors of both companies.